Description Application
ChemicalBook > CAS DataBase List > Argireline

Argireline

Description Application
Product Name
Argireline
CAS No.
616204-22-9
Chemical Name
Argireline
Synonyms
Acetyl Hexapeptide-8;Acetyl Hexapeptide;Reproage;Argreline;Acetylene Hexapeptide-8;Acetyl Hexapeptide-3/Acetyl Hexapeptide-8;AH3P;Akililyn;Akirellin;Argireline
CBNumber
CB41092600
Molecular Formula
C34H60N14O12S
Formula Weight
889
MOL File
616204-22-9.mol
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Argireline Property

Density 
1.54
storage temp. 
-20°C
solubility 
water soluble
solubility 
water soluble
pka
4.43±0.10(Predicted)
form 
lyophilized solid
color 
white
Sequence
Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2
InChI
InChI=1/C34H60N14O12S/c1-17(49)43-20(8-11-25(51)52)29(57)47-22(9-12-26(53)54)31(59)48-23(13-16-61-2)32(60)46-21(7-10-24(35)50)30(58)45-19(6-4-15-42-34(39)40)28(56)44-18(27(36)55)5-3-14-41-33(37)38/h18-23H,3-16H2,1-2H3,(H2,35,50)(H2,36,55)(H,43,49)(H,44,56)(H,45,58)(H,46,60)(H,47,57)(H,48,59)(H,51,52)(H,53,54)(H4,37,38,41)(H4,39,40,42)/t18-,19-,20-,21-,22-,23-/s3
InChIKey
RJZNPROJTJSYLC-LLINQDLYSA-N
SMILES
[C@@H](CCC(=O)N)(NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)C)CCC(=O)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(=O)N)CCCNC(N)=N |&1:0,9,17,26,39,50,r|
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Safety

WGK Germany 
2
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0395
Product name
Ac-EEMQRR-NH2 trifluoroacetate salt
Purity
≥95% (HPLC)
Packaging
1mg
Price
$305
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
COS0000038
Product name
ARGIRELINE
Purity
95.00%
Packaging
1MG
Price
$686
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
COS0000038
Product name
ARGIRELINE
Purity
95.00%
Packaging
5MG
Price
$1830
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
COS0000038
Product name
ARGIRELINE
Purity
95.00%
Packaging
10MG
Price
$3260
Updated
2021/12/16
Crysdot
Product number
CD31001275
Product name
Argireline
Purity
98+%
Packaging
10mg
Price
$152
Updated
2021/12/16
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Argireline Chemical Properties,Usage,Production

Description

Argireline is made up of chains of amino acids. Such chains can affect how our cells work, e.g. relaxing our face muscles. It is derived from the peptide Acetyl hexapeptide-3, a substrate of Botulinum toxin, or more commonly known as Botox.

Application

Botox is a common, anti-wrinkle treatment which is applied using a needle. You may achieve the same anti-aging results with products which contain Argireline. Argireline can help prevent the formation of wrinkles by inhibiting muscle movement in the face. Because of this, Argireline cream is sometimes known as “Botox in a jar.”

Uses

Argireline is an anti-wrinkle peptide. Synthetically produced and considered to be highly effective, clinical studies indicate it can reduce the depth of existing wrinkles. May be incorporated into products marketed as having a topical-BoToX. or “wrinkle-erasing” effect.

benefits

Acetyl Hexapeptide-8 is effectivly reduce various kind of facial wrinkles;Replenish the collagen and polysaccharide, repairthe skin.Winkey patented productin China.It is recommended dosage is 3~10%.

Clinical claims and research

Argireline is a synthetic oligopeptide that emulates the sequence of SNAP-25, a type of SNARE. It has significant skin permeation, interferes with the SNARE ternary complex, and has demonstrated interference with catecholamine release from chromaffin cells. Topical use of 10% argireline resulted in a reduced depth and roughness of periorbital wrinkles in 10 healthy women. One study on 14 volunteers showed that 5% argireline reduced periorbital wrinkles by 32% in 28 days. Most recently, argireline’s efficacy has been measured in 60 Chinese women from a randomized control trial. Its total efficacy was 48.9% compared to 0% in the placebo group, and resulted in significantly decreased wrinkle roughness.

Argireline Preparation Products And Raw materials

Raw materials

Preparation Products

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Argireline Suppliers

MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10658
Advantage
60
Creative Peptides
Tel
Email
info@creative-peptides.com
Country
United States
ProdList
6084
Advantage
56
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4662
Advantage
60
Alfa Chemistry
Tel
+1-5166625404
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
21317
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6393
Advantage
58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19553
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10413
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58
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View Lastest Price from Argireline manufacturers

Wuhan Cell Pharmaceutical Co., Ltd
Product
Argireline/Acetyl Hexapeptide-8 616204-22-9
Price
US $60.00-45.00/g
Min. Order
1g
Purity
>99%
Supply Ability
10000
Release date
2023-09-06
hebei hongtan Biotechnology Co., Ltd
Product
Acetyl Hexapeptide-8 616204-22-9
Price
US $30.00/KG
Min. Order
1KG
Purity
99.9%
Supply Ability
1000
Release date
2024-03-20
Wuhan Haorong Biotechnology Co.,Ltd
Product
Argireline 616204-22-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500
Release date
2023-08-15

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